Dobutamine induced changes in aortic stiffness: influence of obesity in middle aged and elderly individuals with hypertension, diabetes or coronary artery disease
نویسندگان
چکیده
Background Previously, we have shown that increased visceral adiposity was an independent predictor of thoracic aortic wall thickness in elderly individuals at risk for future cardiovascular (CV) events. In this study, we sought to assess the influence of obesity on rest and stress induced changes in aortic stiffness in older individuals with hypertension, diabetes or coronary artery disease at risk for future CV events.
منابع مشابه
Abnormal Stress‐Related Measures of Arterial Stiffness in Middle‐Aged and Elderly Men and Women With Impaired Fasting Glucose at Risk for a First Episode of Symptomatic Heart Failure
BACKGROUND Abnormal resting arterial stiffness is present in middle-aged and elderly persons with abnormalities of fasting glucose (diabetes or impaired fasting glucose) and is associated with exercise intolerance. We sought to determine whether these same persons exhibited stress-related abnormalities of arterial stiffness. METHODS AND RESULTS We analyzed dobutamine magnetic resonance stress...
متن کاملThe Location of Arterial Stiffening Differs in those with Impaired Fasting Glucose versus Diabetes: Implications for Left Ventricular Hypertrophy from the Multi-Ethnic Study of Atherosclerosis
Objective: To determine if middle aged and older individuals with impaired fasting glucose (IFG), but no clinical evidence of cardiovascular disease, exhibit abnormal changes in proximal thoracic aortic stiffness or left ventricular mass when compared to healthy counterparts. Research Design and Methods: From the Multi-Ethnic Study of Atherosclerosis, 2240 subjects with normal fasting glucose (...
متن کاملLocation of Arterial Stiffening Differs in Those With Impaired Fasting Glucose Versus Diabetes
OBJECTIVE To determine whether middle-aged and older individuals with impaired fasting glucose (IFG), but no clinical evidence of cardiovascular disease, exhibit abnormal changes in proximal thoracic aortic stiffness or left ventricular (LV) mass when compared with healthy counterparts. RESEARCH DESIGN AND METHODS From the Multi-Ethnic Study of Atherosclerosis, 2,240 subjects with normal fast...
متن کاملAging reduces left atrial performance during adrenergic stress in middle aged and older patients.
BACKGROUND During adrenergic stress, the influence of age on left atrial (LA) function is unknown. We hypothesized that aging decreases LA total emptying fraction (LAEF) during maximal adrenergic stress. The aim of the study was to determine the influence of aging on LA function during adrenergic stress in middle aged and older patients. METHODS We enrolled 167 middle aged and elderly partici...
متن کاملشیوع و عوامل مرتبط با دیابت نوع دو در شهرستان میبد -1390
Abstract Introdution: Type II diabetes is regarded as the most common form of diabetes. Such factors as genetic history, hypertension, obesity and being overweight involve important risk factors for this disease. Hence, this study aimed to determine the prevalence and associated factors of Type II diabetes within patients aged above 30 years in Meybod. Methods: In this descriptive cross-s...
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عنوان ژورنال:
دوره 15 شماره
صفحات -
تاریخ انتشار 2013